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You are here: Home / Journal Articles / Investigation of an Imported Case of Rabies in a Juvenile Dog with Atypical Presentation / About

Investigation of an Imported Case of Rabies in a Juvenile Dog with Atypical Presentation

By Nicholas Johnson, Alex Nunez, Denise A. Marston, Graeme Harkess, Katja Voller, Trudy Goddard, Daniel Hicks, Lorraine M. Mcelhinney, Anthony R. Fooks

Category Journal Articles
Abstract

Movement of dogs between rabies-endemic and rabies-free countries carries the inherent risk of introducing the disease. In April of 2008, a juvenile dog was imported to the UK from Sri Lanka. It died shortly after transfer to a quarantine facility in the south-east of England following a short history of diarrhoea and convulsions but no overt signs of aggression. Subsequent investigation confirmed that rabies was the cause of death. Rabies virus was isolated from brain samples taken from the dog and the subsequent phylogenetic investigation confirmed that the genomic sequence from this virus shared over 99% homology with endemic rabies viruses from Sri Lanka. Histological examination of the brain demonstrated clear signs of encephalitis and rabies antigenic labeling in numerous neurons. In this particular case, Negri bodies were absent. As this case was diagnosed in a quarantine facility, the ‘rabies-free’ status of the UK was un-affected.

Submitter

Marcy Wilhelm-South

Purdue University

Date 2011
Publication Title Animals
Volume 1
Issue 4
Pages 402-413
Publisher MDPI
DOI 10.3390/ani1040402
URL http://www.mdpi.com/2076-2615/1/4/402
Language English
Additional Language English
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Tags
  1. Animal health and hygiene
  2. Animal welfare
  3. Dogs
  4. Health
  5. Mammals
  6. Quarantine
  7. Rabies
  8. Sri Lanka
  9. Zoonoses