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Chimeras: The ethics of creating human-animal interspecifics
Contributor(s):: Constanze Huther
In summer 2004, I had the pleasure of attending a seminar by Julian Savulescu and Nick Bostrom about "Human Enhancement, Artificial Beings, and the Future of Humanity" at the University of Oxford. Among other quite exotic topics, chimeras were the subject matter of one of our seminar meetings....
Genetic and dietary effects on chicken heterophil function and immune response to Salmonella enteritidis
Contributor(s):: Sarah Beth Redmond, Susan J. Lamont (adviser)
The function of the chicken innate immune system against pathogens is affected by genetic background and immune modulating diet. Heterophils from broiler, Leghorn, and Fayoumi birds showed differential expression of immune genes when stimulated with Salmonella enteritidis (SE) bacteria, a...
Pets: Do They Enhance Our Immunity?
Contributor(s):: Vidhi Desai, Calvin Leung, Ye Rin Lim, Julie M. Fagan
Pets can be highly beneficial to the human health and may even aid in the development of the human immune system. Our study specifically targets the area of pet ownership and its effects on the immune system’s capabilities of different age and ethnic groups. To examine this, we conducted a...
Reduction in mucosal barrier markers with soy protein diet but not Lactobacillus rhamnosus GG in DSS-treated mice
Contributor(s):: Huanyi Jiang, Ruth S. MacDonald (adviser)
Inflammatory bowel disease (IBD) is a common ailment affecting people of all ages. Even though the pathogenesis of IBD has not been fully elucidated, there is evidence that it involves interactions between genetic susceptibility, aberrant activation of the immune system, and the environment....
Whole transcriptome response of chicken spleen and peripheral blood leukocytes to avian pathogenic Escherichia coli
Contributor(s):: Erin Elizabeth Sandford, Susan J. Lamont (adviser)
A greater understanding of the immune response after infection can form the necessary foundation of knowledge needed to enhance immunity through genetic selection. Whole genome microarrays allow for comprehensive analysis of the transcriptome. The transcriptomic responses of spleen and peripheral...