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  1. The effect of isoflurane anaesthesia and buprenorphine on the mouse grimace scale and behaviour in CBA and DBA/2 mice

    Contributor(s):: Miller, A., Kitson, G., Skalkoyannis, B., Leach, M.

    Prevention or alleviation of pain in laboratory mice is a fundamental requirement of in vivo research. The mouse grimace scale (MGS) has the potential to be an effective and rapid means of assessing pain and analgesic efficacy in laboratory mice. Preliminary studies have demonstrated its...

  2. Factors affecting the human attribution of emotions toward animals

    Contributor(s):: Wilkins, A. M., McCrae, L. S., McBride, E. A.

    Attribution of emotions to animals can affect human-animal interactions and dictate animal welfare laws. However, little is known about the factors that influence these attributions. We investigated the effect of belief in animal mind, pet ownership, emotional intelligence, eating orientation,...

  3. Evaluation of a novel rodenticide: acute sub-lethal effects of a methaemoglobin-inducing agent

    Contributor(s):: Quy, R. J., Gibson, T. J., Lambert, M. S., Eason, C. T., Gregory, N. G.

    In a series of experiments the welfare of para-aminovalerophenone (PAVP) sub-lethally poisoned rats ( Rattus norvegicus) was assessed. The experiments: (i) examined the acute methaemoglobin (MetHb) profile over time; (ii) refined the LD50 estimate for PAVP in adult female rats; (iii) developed...

  4. Evaluation of a novel rodenticide: welfare assessment of fatal methaemoglobinaemia in adult rats ( Rattus norvegicus)

    Contributor(s):: Gibson, T. J., Quy, R. J., Eason, C. T., Gregory, N. G.

    This study assessed the welfare of rats ( Rattus norvegicus) poisoned with a lethal dose of the methaemoglobin (MetHb) inducing compound para-aminovalerophenone (PAVP). Twenty rats were orally gavaged with either PAVP (treated) or the vehicle only (control). Spontaneous and evoked behaviours were...

  5. Stereotypic mice are aggressed by their cage-mates, and tend to be poor demonstrators in social learning tasks

    Contributor(s):: Harper, L., Choleris, E., Ervin, K., Fureix, C., Reynolds, K., Walker, M., Mason, G.

    Stereotypic behaviours (SBs) are linked with behavioural inflexibility and resemble symptoms of autism, suggesting that stereotypic animals could have autistic-like social impairments. SBs are also common in caged mice. We therefore hypothesised relationships between stereotypic and social...

  6. c 22 Animals for Research Act

  7. The Psychological Effects of Medical Research on Animal Subjects and the Ramifications for the Applicability of the Research Results

    Contributor(s):: Morgan A. Damm

    Historically, animals have been used in medical research to bring about many of the medical breakthroughs and advances seen today. The successful studies are accompanied by numerous, often concealed, failed studies that are inapplicable to human medicine due to stress and distress changing the...

  8. Antimony: The Use, Rights, and Regulation of Laboratory Animals

    Contributor(s):: Brenda L. Thomas

    'In recent years, the problem, plight, and philosophy behind the use of animals in laboratories, schools, and industries has caused many to formulate an opinion on animal experimentation. It is simple to postulate a Monday morning quarterback philosophy - merely weigh the...

  9. Laboratory Animal Act: A Legislative Proposal

    Contributor(s):: David Favre

    In one recent experiment, mongrel dogs were anesthetized after which thirty-five percent of their body was burned to the third degree by the application of a two hundred degree centigrade hot plate to their skin.' In 1983, researchers at the New Jersey Medical School...

  10. "Nobody Wants to Eat Them Alive:" Ethical Dilemmas and Dual Media Narratives on Domestic Rabbits as Pets and Commodity

    Contributor(s):: Gayane F. Torosyan, Brian Lowe

    Using semiotic analysis, this study explores changes occurring in the societal perception of rabbits as farm animals as juxtaposed to their increasing popularity as domestic companions. This study is based on a preliminary hypothesis that rabbits are increasingly perceived and portrayed in media...

  11. Reinforcement for Operational Mine Detection Rats

    Contributor(s):: Amanda Mahoney, Christophe Cox, Bart Weetjens, Tess Tewelde, Tekimiti Gilbert, Amy Durgin, Alan Poling

    When using animals for the detection of landmines, handlers face challenges of when to reinforce indication responses, as the actual location of landmines in the field is unknown. Anti-Persoonsmijnen Ontmijnende Product Ontwikkeling(Anti-Personnel Landmine Detection Product Development or APOPO)...

  12. Research in Colombia on Explosives Detection by Rats

    Contributor(s):: Luisa Fernando Mendez Pardo, Andres M. Perez-Acosta

    The interdisciplinary research group INVESTUD is investigating the effectiveness of mine-detecting lab rats. In Africa, the APOPO program is well-known for using African giant pouched rats for mine detection, but INVESTUD hopes to build on and even surpass APOPO’s progress to advance...

  13. Two Strategies for Landmine Detection by Giant Pouched Rats

    Contributor(s):: Alan Poling, Christophe Cox, Bart Weetjens, Negussie Beyene, Andrew Sully

    This article compares the performance of Giant African Pouched Rats under two different management systems, both appropriate for mine-detection operational use. Employing International Mine Action Standards for accreditation, the researchers outline the process of conditioning and testing these...

  14. Rabies in Iowa

    Contributor(s):: Bernie Napolski

    Iowa has one of the highest rates of rabies outbreaks in the country and there is very little the state legislature can do about it. To deal with rabies effectively, the state would have to get to the source of the major portion of rabies cases in Iowa - the skunk.

  15. Sep 28 2015

    2015 Animal Ethics Seminar

    A seminar for members of Animal Ethics Committees and their Executive Officers, and animal researchers, is to be held at the Australian Catholic University, North Sydney, on 29 September 2015. The...

    http://habricentral.org/events/details/353

  16. Using Giant African Pouched Rats (Cricetomys Gambianus) to Detect Landmines

    Contributor(s):: Alan Poling, Bart J. Weetjens, Christophe Cox, Negussie W. Beyene, Andrew Sully

    Many species have sensitive chemical-detection systems. For millennia, dogs’ exquisite sense of smell has assisted human beings in hunting and in thwarting intruders. Trained dogs have detected landmines and other explosives, illicit drugs, pipeline leaks, and melanomas (Furton & Myers,...

  17. Pet Pals Therapy

    Pet Pals Therapy are specialists in providing animal therapy to the elderly and adults with learning disabilities. A Pet Pals Therapy session provides service users with a low energy, relaxation based activity programme. Visiting once a month, Pet Pals Therapy provides an hour session using a...

  18. Indoor Environmental Exposures and Exacerbation of Asthma: An Update to the 2000 Review by the Institute of Medicine

    Contributor(s):: Kanchongkittiphon, Watcharoot, Mendell, Mark J., Gaffin, Jonathan M., Wang, Grace, Phipatanakul, Wanda

  19. Pleeease mommy, can I have one?

    Contributor(s):: Pfaff, Leslie Garisto

  20. Gathering food from rodent nests in Siberia

    Contributor(s):: Ståhlberg, Sabira