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The effects of chronic exposure to common bedding materials on the metabolic rate and overall health of male CD-1 mice

By C. E. Becker, C. F. Mathur, B. G. Rehnberg

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Abstract

Anecdotes and personal Web pages claim that cedar and pine beddings cause respiratory distress in rodents, although no previous research could be found to support these claims. There have, however, been published studies of respiratory distress in cedar and pine mill workers. That research links exposure to wood dust to asthma and to bronchial and alveolar damage in humans. This study looks at the effects of 3 types of bedding (CareFRESHReg.Original, cedar, and pine) on the growth, food intake, oxygen consumption, IgE antibody concentrations, and general appearance and behavior in male CD-1 mice. Mice who were housed on these beddings for approximately 4 months did not show significant differences in any of these variables. This suggests that these 3 materials provide equally healthy substrates for long-term rearing of mice and possibly other rodents.

Publication Title Journal of Applied Animal Welfare Science
Volume 13
Issue 1
Pages 46-55
ISBN/ISSN 1088-8705
Publisher Taylor & Francis
DOI 10.1080/10888700903372010
Language English
Author Address Department of Biological Sciences, York College of Pennsylvania, York, PA 17405-7199, USA.brehnber@ycp.edu
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Tags
  1. Animal behavior
  2. Animal diseases
  3. Animal rights
  4. Animals
  5. Animal welfare
  6. Antibodies
  7. Asthma
  8. Behavior and behavior mechanisms
  9. Blood
  10. Dust
  11. Effect
  12. Feed intake
  13. Health
  14. Humans
  15. Lung diseases
  16. Mammals
  17. Men
  18. Metabolism
  19. Mice
  20. Nutrition
  21. oxygen consumption
  22. peer-reviewed
  23. Primates
  24. Research
  25. respiratory diseases
  26. respiratory system
  27. Rodents
  28. Studies
  29. substrates
  30. vertebrates
  31. wood
Badges
  1. peer-reviewed