You are here: Home / Journal Articles / How Can Systematic Reviews Teach Us More about the Implementation of the 3Rs and Animal Welfare? / About

How Can Systematic Reviews Teach Us More about the Implementation of the 3Rs and Animal Welfare?

By Merel Ritskes-Hoitinga, Judith van Luijk

Category Journal Articles
Abstract

This paper describes the introduction of the systematic review methodology in animal-based research and the added value of this methodology in relation to the 3Rs and beyond. The 3Rs refer to Replacement, Reduction, and Refinement of animal studies. A systematic review (SR) is defined as a literature review focused on a single question that tries to identify, appraise, select, and synthesise all high-quality research evidence relevant to that question. Examples are given on how SRs lead to the implementation of the 3Rs and better science. Additionally, a broader context is given regarding societal, political, and scientific developments. Various examples of systematic reviews are given to illustrate the current situation regarding reporting, quality, and translatability of animal-based research. Furthermore, initiatives that have emerged to move further towards more responsible and sustainable research is of benefit for both animals and humans.

Submitter

Marcy Wilhelm-South

Purdue University

Date 2019
Publication Title Animals
Volume 9
Issue 12
Pages 9
Publisher MDPI
DOI 10.3390/ani9121163
URL https://www.mdpi.com/2076-2615/9/12/1163
Language English
Additional Language English
Cite this work

Researchers should cite this work as follows:

Tags
  1. Animal welfare
  2. Evidence
  3. open access
  4. Research
  5. systematic reviews
Badges
  1. open access