How Can Systematic Reviews Teach Us More about the Implementation of the 3Rs and Animal Welfare?
| Category | Journal Articles |
|---|---|
| Abstract |
This paper describes the introduction of the systematic review methodology in animal-based research and the added value of this methodology in relation to the 3Rs and beyond. The 3Rs refer to Replacement, Reduction, and Refinement of animal studies. A systematic review (SR) is defined as a literature review focused on a single question that tries to identify, appraise, select, and synthesise all high-quality research evidence relevant to that question. Examples are given on how SRs lead to the implementation of the 3Rs and better science. Additionally, a broader context is given regarding societal, political, and scientific developments. Various examples of systematic reviews are given to illustrate the current situation regarding reporting, quality, and translatability of animal-based research. Furthermore, initiatives that have emerged to move further towards more responsible and sustainable research is of benefit for both animals and humans. |
| Submitter |
Purdue University |
| Date | 2019 |
| Publication Title | Animals |
| Volume | 9 |
| Issue | 12 |
| Pages | 9 |
| Publisher | MDPI |
| DOI | 10.3390/ani9121163 |
| URL | https://www.mdpi.com/2076-2615/9/12/1163 |
| Language | English |
| Additional Language | English |
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