Evaluation of pharmacokinetics and efficacy of ivermectin following oral administration in dogs against experimental infection of Ctenocephalides felis felis and Rhipicephalus sanguineus
Contributor(s):: Magalhaes, V. S., Cid, Y. P., Ferreira, T. P., Medeiros, D. M. V., Batista, L. C. de S. O., Correia, T. R., Albert, A. L. M., Scott, F. B.
With the increasing number of pets in home the human-animal relationship is increasingly close and care about control disease growing. Ivermectin (IVM) is frequently used because its proven safety. IVM is recommended for the treatment of demodectic scabies and prevention of heartworm in dogs, but...
Anesthesia in some categories of patients and clinical conditionsAnestesia in alcune categorie di pazienti e condizioni cliniche
Contributor(s):: Grazioli, O.
The author analyses anesthesia in the most frequent and risky clinical conditions, for which greater knowledge and attention in anesthetic management are required. In the final part, euthanasia is taken into account, because of its strategic importance, with emotional and psychological aspects...
Assessment of acute pain in cats: signs, tools and limitations
Contributor(s):: White, K. L.
Recent advances in pain assessment in companion animals represent a tenacious, painstaking and time-consuming dedication to improving animal welfare. Attitudes and knowledge about pain assessment, particularly in cats, have changed dramatically in the past few decades, representing a very obvious...
A dermatologist's viewpoint on the significance of the human-animal bond in practice
Contributor(s):: Liska, D. A.
Feline aggression directed toward people: causes and treatment
Contributor(s):: Horwitz, D. F.
Effect of gender and halothane genotype on cognitive bias and its relationship with fear in pigs
Contributor(s):: Carreras, R., Arroyo, L., Mainau, E., Pena, R., Bassols, A., Dalmau, A., Faucitano, L., Manteca, X., Velarde, A.
Cognitive bias (CB) has been recently proposed as a tool to study emotions by assessing the cognitive function through behaviour observation. It is based on the premise that subjects in a negative affective state perform more negative judgements about ambiguous stimuli than subjects in positive...
Determination of residue levels of alpha-chloralose in duck tissues
Contributor(s):: Goldade, David A., Stahl, Randal S., Johnston, John J.
The effect of isoflurane anaesthesia and buprenorphine on the mouse grimace scale and behaviour in CBA and DBA/2 mice
Contributor(s):: Miller, A., Kitson, G., Skalkoyannis, B., Leach, M.
Prevention or alleviation of pain in laboratory mice is a fundamental requirement of in vivo research. The mouse grimace scale (MGS) has the potential to be an effective and rapid means of assessing pain and analgesic efficacy in laboratory mice. Preliminary studies have demonstrated its...
Sep 28 2015
2015 Animal Ethics Seminar
Sep 01 2015
12th World Congress of Veterinary Anaesthesiology
Rat aversion to sevoflurane and isoflurane
Contributor(s):: Bertolus, J. B., Nemeth, G., Makowska, I. J., Weary, D. M.
Virtually all rodents used in research are eventually euthanized. Best practice is to anaesthetize these animals before euthanasia using a halogenated anaesthetic such as isoflurane. Exposure to isoflurane is aversive, but less so than exposure to the commonly used carbon dioxide. Sevoflurane is...
Testing three measures of mouse insensibility following induction with isoflurane or carbon dioxide gas for a more humane euthanasia
Contributor(s):: Moody, C. M., Makowska, I. J., Weary, D. M.
Laboratory mice are commonly killed via exposure to gradually increasing concentrations of isoflurane and carbon dioxide (CO 2) gas. Once rendered insensible using isoflurane or CO 2, a high concentration of CO 2 is used to decrease time to death. When the switch from isoflurane to a high flow...
Tales about tails: is the mutilation of animals justifiable in their best interests or in ours?
Contributor(s):: Edwards, S., Bennett, P., Appleby, M. C., Weary, D. M., Sandoe, P.
Tail docking, involving surgical or non-surgical removal of a portion of the tail, is one of the most widely carried out and contentious mutilations inflicted by humans on animals. To differing extents, this procedure is carried out on farm livestock, draught animals and companion animals. The...
Do rubber rings coated with lignocaine reduce the pain associated with ring castration of lambs?
Contributor(s):: Stewart, M., Beausoleil, N. J., Johnson, C. B., Webster, J. R., Schutz, K. E., Cox, N., Stafford, K. J.
To facilitate the wider use of pain relief on-farm, practical 'farmer friendly' methods for administering pain relief are necessary. This proof of concept study evaluated the efficacy of rubber rings coated with local anaesthetic (LA, lignocaine) for providing pain relief in lambs castrated 4...
Evaluation of microwave energy as a humane stunning technique based on electroencephalography (EEG) of anaesthetised cattle
Contributor(s):: Rault, J. L., Hemsworth, P. H., Cakebread, P. L., Mellor, D. J., Johnson, C. B.
Humane slaughter implies that an animal experiences minimal pain and distress before it is killed. Stunning is commonly used to induce insensibility but can lead to variable results or be considered unsatisfactory by some religious groups. Microwave energy can induce insensibility in rats, and...
Humane killing of nonhuman animals for disease control purposes
Contributor(s):: Raj, M.
Reports and guidelines produced by international institutions such as the World Organization for Animal Health (OIE, 2005) describe various methods of killing nonhuman animals. Selection and implementation of a killing method may involve several factors. Preventing or minimizing risk to human...
Training large macaws for artificial insemination procedures
Contributor(s):: Leblanc, F., Pothet, G., Jalme, M. S., Dorval, M., Bovet, D.
For some endangered parrot species, captive breeding may be the only insurance for their survival. However, many individuals in captivity do not reproduce. Artificial insemination (AI) may help overcome reproductive failures or geographic distance. For semen collection in birds, massage is the...
Impact of inhalation anaesthesia, surgery and analgesic treatment on home cage behaviour in laboratory mice
Contributor(s):: Cesarovic, N., Arras, M., Jirkof, P.
Anaesthesia and analgesia are used frequently in laboratory routine to ensure animal welfare and good scientific outcomes in experiments that may elicit pain or require immobilisation of the animal. However, there is concern regarding the effect of these procedures on animal behaviour in...
Mouse aversion to isoflurane versus carbon dioxide gas
Contributor(s):: Moody, C. M., Weary, D. M.
Isoflurane and carbon dioxide (CO 2) gas are used for rodent euthanasia. This study compared mouse aversion to isoflurane versus gradual-fill CO 2 gas, and compared two methods of isoflurane delivery: vaporizer and drop. Mouse acclimation to a light-dark apparatus was used to create a light...
Behavioural assessment of dental pain in captive Malayan sun bears ( Helarctos malayanus)
Contributor(s):: Fleming, M., Burn, C. C.
Captive bears are prone to developing dental pathology for reasons including longevity in captivity, inappropriate diet, trauma, and stereotypical bar biting. If not detected, this can cause pain and suffering, with negative welfare consequences. As animals cannot verbally express feelings,...