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  1. Relationship between behavioural tests and agonistic interactions at different age levels in pigs

    Contributor(s):: Scheffler, K., Stamer, E., Traulsen, I., Krieter, J.

    Fighting among pigs is a normal behavioural pattern to establish a stable rank order. Enhanced aggressive behaviour in pigs in groups lead to increasing stress and injuries especially in mixing situations used as a common procedure in modern pig production systems. In such systems, it is usually...

  2. Does environmental enrichment promote recovery from stress in rainbow trout?

    Contributor(s):: Pounder, K. C., Mitchell, J. L., Thomson, J. S., Pottinger, T. G., Buckley, J., Sneddon, L. U.

    The EU Directive on animal experimentation suggests that all protected animals should have enrichment to improve welfare yet relatively little research has been conducted on the impact of enrichment in fish. Studies employing enrichment in zebrafish have been contradictory and all fish species...

  3. Manifestation of neuronal ceroid lipofuscinosis in Australian Merino sheep: observations on altered behaviour and growth

    Contributor(s):: Cronin, G. M., Beganovic, D. F., Sutton, A. L., Palmer, D. J., Thomson, P. C., Tammen, I.

    Neuronal ceroid lipofuscinoses (NCL) is an inherited neurodegenerative disorder in children. Presently there is no effective treatment and the disorder is lethal. NCL occur in a variety of non-human species including sheep, which are recognised as valuable large animal models for NCL. This...

  4. The effects of metabolic cage housing and sex on cognitive bias expression in rats

    Contributor(s):: Barker, T. H., Howarth, G. S., Whittaker, A. L.

    The use of metabolic cages is established housing protocol in small-animal, gastrointestinal research. Physiological data, as primarily observed through secretions of the hypothalamic-pituitary-adrenal axis has shown that rodents housed in this manner experience an increased stress response. Few...

  5. Experimental control for the ovariectomized rat model: use of sham versus nonmanipulated animal

    Contributor(s):: Kruger, M. C., Morel, P. C. H.

    One of 2 models required by the U.S. Food and Drug Administration for registration of a treatment for osteoporosis, the ovariectomized (OVX) rat model, is widely used in scientific studies investigating sex hormone-deficient bone loss. The use of control nonhuman animals is critical because bone...

  6. Effects of stereotypic behaviour and chronic mild stress on judgement bias in laboratory mice

    Contributor(s):: Novak, J., Stojanovski, K., Melotti, L., Reichlin, T., Palme, R., Wurbel, H.

    Cognitive processes are influenced by underlying affective states, and tests of cognitive bias have recently been developed to assess the valence of affective states in animals. These tests are based on the fact that individuals in a negative affective state interpret ambiguous stimuli more...

  7. The Social Contract, the Conservative Attitude, and Antibiotics Development

    Contributor(s):: Weber, Eli

  8. The effect of isoflurane anaesthesia and buprenorphine on the mouse grimace scale and behaviour in CBA and DBA/2 mice

    Contributor(s):: Miller, A., Kitson, G., Skalkoyannis, B., Leach, M.

    Prevention or alleviation of pain in laboratory mice is a fundamental requirement of in vivo research. The mouse grimace scale (MGS) has the potential to be an effective and rapid means of assessing pain and analgesic efficacy in laboratory mice. Preliminary studies have demonstrated its...

  9. Evaluation of a novel rodenticide: acute sub-lethal effects of a methaemoglobin-inducing agent

    Contributor(s):: Quy, R. J., Gibson, T. J., Lambert, M. S., Eason, C. T., Gregory, N. G.

    In a series of experiments the welfare of para-aminovalerophenone (PAVP) sub-lethally poisoned rats ( Rattus norvegicus) was assessed. The experiments: (i) examined the acute methaemoglobin (MetHb) profile over time; (ii) refined the LD50 estimate for PAVP in adult female rats; (iii) developed...

  10. Evaluation of a novel rodenticide: welfare assessment of fatal methaemoglobinaemia in adult rats ( Rattus norvegicus)

    Contributor(s):: Gibson, T. J., Quy, R. J., Eason, C. T., Gregory, N. G.

    This study assessed the welfare of rats ( Rattus norvegicus) poisoned with a lethal dose of the methaemoglobin (MetHb) inducing compound para-aminovalerophenone (PAVP). Twenty rats were orally gavaged with either PAVP (treated) or the vehicle only (control). Spontaneous and evoked behaviours were...

  11. Stereotypic mice are aggressed by their cage-mates, and tend to be poor demonstrators in social learning tasks

    Contributor(s):: Harper, L., Choleris, E., Ervin, K., Fureix, C., Reynolds, K., Walker, M., Mason, G.

    Stereotypic behaviours (SBs) are linked with behavioural inflexibility and resemble symptoms of autism, suggesting that stereotypic animals could have autistic-like social impairments. SBs are also common in caged mice. We therefore hypothesised relationships between stereotypic and social...

  12. Urinary posture and motor laterality in dogs ( Canis lupus familiaris) at two shelters

    Contributor(s):: Gough, W., McGuire, B.

    Motor laterality is the preference shown for using one limb or lateral half of the body over the other. In domestic dogs, most laterality studies have examined forelimb preferences during staged tasks. We focused instead on hindlimb preferences during urination when males use the raised-leg...

  13. Exploring the canine mind: Studies of dog cognition

    Contributor(s):: Macpherson, Krista, Roberts, William A.

  14. Refinement of welfare through development of a quantitative system for assessment of lifetime experience

    Contributor(s):: Wolfensohn, S., Sharpe, S., Hall, I., Lawrence, S., Kitchen, S., Dennis, M.

    This paper proposes a system that uses intrinsic study data to provide a clear visualisation of the stresses involved during the animal's life history that can be applied to all types of studies, even those not requiring invasive techniques. Thus, it provides an opportunity for researchers to...

  15. Playful handling of laboratory rats is more beneficial when applied before than after routine injections

    Contributor(s):: Cloutier, S., Wahl, K. L., Panksepp, J., Newberry, R. C.

    The ability of positive affective states to counteract negative states engendered by routine medical procedures remains poorly studied. In laboratory rats, positive affect typically associated with rough-and-tumble play can be induced through human "hand play" - the experience of being "tickled"...

  16. The power of automated behavioural homecage technologies in characterizing disease progression in laboratory mice: a review

    Contributor(s):: Richardson, C. A.

    Behavioural changes that occur as animals become sick have been characterized in a number of species and include the less frequent occurrence of 'luxury behaviours' such as playing, grooming and socialization. 'Sickness behaviours' or behavioural changes following exposure to infectious agents,...

  17. Clinical animal behaviour models of stereotypic behaviour and underlying cognition

    Contributor(s):: Daniel Mills

    Bizarre repetitive behaviour may be quite common, with estimates in people and dogs of a prevalence of up to 8%. Whereas these are often considered important indicators of mental health problems in people, in companion animals, many owners view these behaviours as "quirky" or even...

  18. Evaluation of microwave energy as a humane stunning technique based on electroencephalography (EEG) of anaesthetised cattle

    Contributor(s):: Rault, J. L., Hemsworth, P. H., Cakebread, P. L., Mellor, D. J., Johnson, C. B.

    Humane slaughter implies that an animal experiences minimal pain and distress before it is killed. Stunning is commonly used to induce insensibility but can lead to variable results or be considered unsatisfactory by some religious groups. Microwave energy can induce insensibility in rats, and...

  19. Is Counseling Going to the Dogs? An Exploratory Study Related to the Inclusion of an Animal in Group Counseling with Adolescents

    Contributor(s):: Lange, Amber M., Cox, Jane A., Bernert, Donna J., Jenkins, Christie D.

  20. Distribution of nonhuman animal versus nonanimal research funding at four U.S. Institutions in fiscal year 2000

    Contributor(s):: Bogle, R., Greek, R.

    Much controversy exists concerning the use of nonhuman animals in biomedical research. Textbooks, articles, and journals are dedicated to studying animal models, studying alternatives, and debating various aspects of the issue. Surprisingly however, very little information exists on how many...