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Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice
| Contributor(s):: Brigman, Jonathan L., Mathur, Poonam, Harvey-White, Judith, Izquierdo, Alicia, Saksida, Lisa M., Bussey, Timothy J., Fox, Stephanie, Deneris, Evan, Murphy, Dennis L., Holmes, Andrew
Growing evidence supports a major contribution of cortical serotonin (5-hydroxytryptamine, 5-HT) to the modulation of cognitive flexibility and the cognitive inflexibility evident in neuropsychiatric disorders. The precise role of 5-HT and the influence of 5-HT gene variation in mediating this...
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Recent developments in the use of animal models of psychiatric disease: Introduction to special issue
| Contributor(s):: Fisch, Gene S., Holmes, Andrew
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Effects of selection for cooperation and attention in dogs
| Contributor(s):: Gácsi, Márta, McGreevy, Paul, Kara, Edina, Miklósi, Ádám
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Kind granddaughters of angry grandmothers: The effect of domestication on vocalization in cross-bred silver foxes
| Contributor(s):: Gogoleva, Svetlana S., Volodin, Ilya A., Volodina, Elena V., Kharlamova, Anastasia V., Trut, Lyudmila N.
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Phenotyping of aggressive behavior in Golden Retriever dogs with a questionnaire
| Contributor(s):: van den Berg, L., Schilder, M. B. H., de Vries, H., Leegwater, P. A. J., van Oost, B. A.
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Behavior Genetics of Canine Aggression: Behavioral Phenotyping of Golden Retrievers by Means of an Aggression Test
| Contributor(s):: van den Berg, L., Schilder, M. B. H., Knol, B. W.
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Phenotyping mouse chromosome substitution strains reveal multiple QTLs for febrile seizure susceptibility
| Contributor(s):: Hessel, E. V. S., van Gassen, K. L. I., Wolterink-Donselaar, I. G., Stienen, P. J., Fernandes, C., Brakkee, J. H., Kas, M. J. H., de Graan, P. N. E.
Febrile seizures (FS) are the most common seizure type in children and recurrent FS are a risk factor for developing temporal lobe epilepsy. Although the mechanisms underlying FS are largely unknown, recent family, twin and animal studies indicate that genetics are important in FS...
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T-maze behaviour in broiler chicks is not sensitive to right-left preferences, test order or time-of-day
| Contributor(s):: Marin, R. H., Jones, R. B.
240 newly hatched, mixed-sex broiler chicks were randomly allocated to 12 groups of 20. At 2 days of age, a group of 20 chicks was placed in the brood area of each of 2 T-mazes at 08:30 h; the brood areas were positioned on either side of maze. After acclimatization, one chick from each group was...
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Influence of mothering on emotional and social reactivity of domestic pullets
| Contributor(s):: Perre, Y., Wauters, A. M., Richard-Yris, M. A.
The aim of this study was to determine whether different early mothering experiences influenced emotional and social reactivity of sub-adults and adults in domestic fowl. We compared two types of individuals: brooded and non-brooded pullets. Brooded pullets were reared by a maternal hen during...
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Investigations on genetic disease resistance in swine - a contribution to the reduction of pain, suffering and damage in farm animals.
| Contributor(s):: Reiner, G.
This review deals with genetic disease resistance in pigs as a prospective opportunity to reduce pain, suffering and damage in swine production. Even under favourable terms of housing and management, infectious diseases are wide-spread, and have to be ranked among the major sources for suffering...
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Mother-offspring bonding in farmed red deer: accuracy of visual observation verified by DNA analysis
| Contributor(s):: Vankova, D., Bartos, L., Cizova-Schroffelova, D., Nespor, F., Jandurova, O.
The accuracy of a maternity assessment based on visual observation was tested during the post parturient phase in farmed red deer in Czech Republic [date not given]. The mother of the calf was determined using visual observation of the hind's peri-parturient and early maternal behaviour during...
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All a mother's fault? Transmission of stereotypy in striped mice Rhabdomys
| Contributor(s):: Jones, M., Lierop, M. van, Pillay, N.
Environmentally induced stereotypy is the most common abnormal behaviour in captive animals. However, not all animals housed in identically impoverished environments develop stereotypy, possibly because of differences in genetic predisposition. To investigate the transmission of stereotypy in...
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Increased reproductive output in stereotypic captive Rhabdomys females: potential implications for captive breeding
| Contributor(s):: Jones, M. A., Lierop, M. van, Mason, G., Pillay, N.
Captive animal populations can diverge considerably from populations in the wild, despite the animals not being deliberately domesticated. If the phenotypes which are of benefit in captivity are heritable, the genotypes of captive-stock can diverge swiftly and substantially from wild-stock. Using...
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Genetic analysis of reactivity to humans in Goettingen minipigs
| Contributor(s):: Kohn, F., Sharifi, A. R., Simianer, H.
Goettingen minipigs are laboratory animals with an increasing demand over the last few years. At the moment, Goettingen minipigs are not selected for a low reactivity to humans and this trait is not included in the breeding programme. However, it is obvious that there is a need for genetically...
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The presence of the dam during handling prevents the socialization of young calves to humans
| Contributor(s):: Krohn, C. C., Boivin, X., Jago, J. G.
The effect of handling and hand-feeding of calves with or without their dams present on the calves' subsequent response to humans was investigated using 5 groups of 10 Danish Friesian calves, each of which received a different treatment. The treatments were: calf separated from its dam...
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The influence of rearing on personality ratings of captive chimpanzees ( Pan troglodytes ). (Special issue: Primates in zoos)
| Contributor(s):: Martin, J. E.
Personality traits of 43 captive chimpanzees (Pan troglodytes) at five zoos in the United Kingdom were assessed. Chimpanzees were categorized into one of three rearing conditions: mother-group-reared (MGR), reared with others but separated from mother (RO), and reared alone for a period of time...
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Effect of male-to-male aggressiveness and feed-restriction during rearing on sexual behaviour and aggressiveness towards females by male domestic fowl
| Contributor(s):: Millman, S. T., Duncan, I. J. H.
This experiment was one part of a larger study investigating problems of aggression towards females by male broiler breeder fowl. To investigate causal mechanisms, we were interested in determining (1) if feed-restriction during rearing affects behaviour towards females at sexual maturity and (2)...
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A behaviour test on German Shepherd dogs: heritability of seven different traits
| Contributor(s):: Ruefenacht, S., Gebhardt-Henrich, S., Miyake, T., Gaillard, C.
In this study, genetic and non-genetic effects on behavioural traits were estimated, based on records of the field behaviour test of the Swiss German Shepherd Dog breeding club. This standardized test has been applied since 1949 and comprised the following seven traits: self-confidence, nerve...
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Indication of a genetic basis of stereotypies in laboratory-bred bank voles ( Clethrionomys glareolus )
| Contributor(s):: Schoenecker, B., Heller, K. E.
The development of stereotypies was studied in 2 successive laboratory-bred generations of bank voles representing F1 (n=248) and F2 (n=270) of an originally wild caught stock. It was shown that the propensity to develop stereotypies under barren housing conditions strongly relates to the same...
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Stereotypic behaviour is genetically transmitted in the African striped mouse Rhabdomys pumilio
| Contributor(s):: Schwaibold, U., Pillay, N.
The development of stereotypic behaviour was studied in captive striped mice, Rhabdomys pumilio. Based on the findings of previous studies, it was hypothesized that there is a genetic basis of stereotypy in striped mice. Breeding and cross-fostering experiments were used to test this hypothesis....
