Genetic and dietary effects on chicken heterophil function and immune response to Salmonella enteritidis
Contributor(s):: Sarah Beth Redmond, Susan J. Lamont (adviser)
The function of the chicken innate immune system against pathogens is affected by genetic background and immune modulating diet. Heterophils from broiler, Leghorn, and Fayoumi birds showed differential expression of immune genes when stimulated with Salmonella enteritidis (SE) bacteria, a...
Reduction in mucosal barrier markers with soy protein diet but not Lactobacillus rhamnosus GG in DSS-treated mice
Contributor(s):: Huanyi Jiang, Ruth S. MacDonald (adviser)
Inflammatory bowel disease (IBD) is a common ailment affecting people of all ages. Even though the pathogenesis of IBD has not been fully elucidated, there is evidence that it involves interactions between genetic susceptibility, aberrant activation of the immune system, and the environment....
Whole transcriptome response of chicken spleen and peripheral blood leukocytes to avian pathogenic Escherichia coli
Contributor(s):: Erin Elizabeth Sandford, Susan J. Lamont (adviser)
A greater understanding of the immune response after infection can form the necessary foundation of knowledge needed to enhance immunity through genetic selection. Whole genome microarrays allow for comprehensive analysis of the transcriptome. The transcriptomic responses of spleen and peripheral...