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  1. Buprenorphine via drinking water and combined oral-injection protocols for pain relief in mice

    Contributor(s):: Sauer, Mareike, Fleischmann, Thea, Lipiski, Miriam, Arras, Margarete, Jirkof, Paulin

    Buprenorphine is the opioid analgesic most commonly used in laboratory mice. However, to maintain therapeutically effective serum levels, repeated injections are required. To overcome negative aspects of restraint and injection, oral self-administration is a promising alternative but has been...

  2. Using the mouse grimace scale and behaviour to assess pain in CBA mice following vasectomy

    Contributor(s):: Miller, Amy L., Kitson, Gemma L., Skalkoyannis, Benjamin, Flecknell, Paul A., Leach, Matthew C.

    Mice used in biomedical research should have pain reduced to an absolute minimum through refinement of procedures or by the provision of appropriate analgesia. Vasectomy is a common and potentially painful surgical procedure carried out on male mice to facilitate the production of genetically...

  3. Effects of analgesic intervention on behavioural responses to Low Atmospheric Pressure Stunning

    Contributor(s):: Martin, Jessica E., Christensen, Karen, Vizzier-Thaxton, Yvonne, McKeegan, Dorothy E. F.

    Worldwide, more than 50 billion chickens are killed annually for food production so their welfare at slaughter is an important concern. Low Atmospheric Pressure Stunning (LAPS) is a novel approach to pre-slaughter stunning of poultry in which birds are rendered unconscious by gradually reducing...

  4. Assessment of pain responses associated with castration of 10-week-old lambs using the Callicrate 'WEE Bander' compared with a standard elastrator

    Contributor(s):: Jongman, Ellen C., Borg, Samantha, Hemsworth, Paul H.

    Castration of ram lambs is a standard procedure to facilitate animal management, however all methods of castration used in the lamb industry are considered to be painful based on behavioural and physiological responses. This experiment compares an alternative method of ring castration (Callicrate...

  5. Effect of analgesic strategies on pain behaviour associated with combined ring castration and hot iron tail docking in Merino lambs

    Contributor(s):: Kells, Nikki J., Beausoleil, Ngaio J., R Godfrey, A. Jonathan, E Littlewood, Katherine, Ward, R. Neil, Johnson, Craig B.

    Most countries don’t require analgesia to be provided to lambs

  6. tool to measure impact of AAP for refugees or PTSD/anxiety

    Forum › general-discussion › hcdiscussions

    Hi group,    I am looking for any pre-existing tools to measure the impact of AAP with refugees or a PTSD or anxiety measuring tool combined with AAP. please email blalockb@bc.edu...


  7. Behavioural and physiological responses to clove oil injected under the horn bud of calves

    Contributor(s):: Sutherland, Mhairi A., Larive, Johan, Cave, Vanessa, Zobel, Gosia

    The aim of this study was to evaluate the acute and longer-term behavioural and physiological responses caused by administering clove oil under the horn bud of calves and compare these with the responses caused by cautery disbudding. Forty female Friesian-cross calves (mean +/- SD: 3.5 +/- 2.72 d...

  8. Initial evaluation of facial expressions and behaviours of harbour seal pups (Phoca vitulina) in response to tagging and microchipping

    Contributor(s):: MacRae, Amelia Mari, Joanna Makowska, I., Fraser, David

    There are no proven species-specific indicators of pain in harbour seals (Phoca vitulina). The analysis of facial expressions has proven to be a repeatable, accurate and valid method of identifying pain in multiple species, but facial expressions have not been examined in any species of pinniped....

  9. Tramadol:Paracetamol in drinking water for treatment of post-surgical pain in laboratory mice

    Contributor(s):: Jirkof, Paulin, Arras, Margarete, Cesarovic, Nikola

    In the search for stress-free analgesia administration for laboratory mice suffering pain, oral delivery of Tramadol:Paracetamol (T:P) shows great promise. Here, we monitored the analgesic efficacy and side effects of a T:P combination administered solely in the drinking water of female C57BL/6J...

  10. Evaluation of alternatives to cautery disbudding of dairy goat kids using behavioural measures of post-treatment pain

    Contributor(s):: Hempstead, Melissa N., Waas, Joseph R., Stewart, Mairi, Cave, Vanessa M., Sutherland, Mhairi A.

    Alternatives to cautery disbudding (caustic paste and cryosurgical disbudding, and clove oil injection) were evaluated using behavioural measures of post-treatment pain in dairy goat kids. Fifty Saanen doe kids were randomly assigned to one of five treatments (n = 10/treatment): (i) cautery...

  11. Dairy cows under experimentally-induced Escherichia coli mastitis show negative emotional states assessed through Qualitative Behaviour Assessment

    Contributor(s):: de Boyer des Roches, Alice, Lussert, Alexandra, Faure, Marion, Herry, Vincent, Rainard, Pascal, Durand, Denys, Wemelsfelder, Françoise, Foucras, Gilles

    Mastitis and associated pain have been identified as a major health and welfare problem affecting dairy cows, however little is known about how cows emotionally experience this illness. Qualitative behaviour assessment (QBA) is a 'whole animal' methodology for assessing animal emotion, through...

  12. Evaluating environmental enrichment as a method to alleviate pain after castration and tail docking in pigs

    Contributor(s):: Backus, Brittany L., McGlone, John J.

    Castration and tail docking are common management practices performed on commercial swine farms in the US and around the world to reduce adverse behaviors and the occurrence of boar taint. However, these practices themselves are a welfare concern for the piglet because they cause acute...

  13. Controlled clinical trial of canine therapy versus usual care to reduce patient anxiety in the emergency department

    Contributor(s):: Kline, J. A., Fisher, M. A., Pettit, K. L., Linville, C. T., Beck, A. M.

  14. Why Pain Is Still a Welfare Issue for Farm Animals, and How Facial Expression Could Be the Answer

    Full-text: Available

    | Contributor(s):: Krista Marie McLennan

    Pain is a sensory and emotional experience that significantly affects animal welfare and has negative impacts on the economics of farming. Pain is often associated with common production diseases such as lameness and mastitis, as well as introduced to the animal through routine husbandry...

  15. Conceptual and methodological issues relating to pain assessment in mammals: The development and utilisation of pain facial expression scales

    | Contributor(s):: McLennan, Krista M., Miller, Amy L., Dalla Costa, Emanuela, Stucke, Diana, Corke, Murray J., Broom, Donald M., Leach, Matthew C.

  16. Bundling Interventions to Enhance Pain Care Quality (BITE Pain) in Medical Surgical Patients

    | Contributor(s):: Rice, K. L., Castex, J., Redmond, M., Burton, J., Guo, J. W., Beck, S. L.

  17. Perception de la souffrance, empathie inter-espèces et régimes d'interactivité

    Full-text: Available

    | Contributor(s):: Veronique Servais

    La perception de la souffrance animale dépend de l’empathie et celle-ci fait l’objet d’un biais « intra-groupe » chez l’humain. On le retrouve dans le cas de l’empathie inter-espèces : la réponse varie en...

  18. Goals of Care: Development and Use of the Serious Veterinary Illness Conversation Guide

    | Contributor(s):: Goldberg, K. J.

  19. Tail Docking of Canine Puppies: Reassessment of the Tail's Role in Communication, the Acute Pain Caused by Docking and Interpretation of Behavioural Responses

    Full-text: Available

    | Contributor(s):: David J Mellor

    Laws, regulations and professional standards increasingly aim to ban or restrict non-therapeutic tail docking in canine puppies. These constraints have usually been justified by reference to loss of tail participation in communication between dogs, the acute pain presumed to be caused during...

  20. Animal-assisted therapy for inpatient adults

    | Contributor(s):: Phung, A.