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  1. Scientific Validation of Cannabidiol for Management of Dog and Cat Diseases

    Contributor(s):: Alvarenga, Isabella Corsato, Panickar, Kiran S., Hess, Hannah, McGrath, Stephanie

  2. Pharmacokinetics and Pharmacodynamics of Immediate- and Modified-Release Mycophenolic Acid Preparations in Healthy Beagle Dogs

    Full-text: Available

    | Contributor(s):: Michael Klotsman, Sebastien Coquery, Gayatri Sathyan, Vatsala Naageshwaran, Paddy Shivanand, Amanda J. Fairchild4, Amanda J. Fairchild, Oliver A. Garden, Wayne H. Anderson

    Background: Mycophenolic acid (MPA) is a broad-acting immunomodulating agent that may be therapeutically beneficial for the treatment of immune-mediated diseases in canine patients. Objectives: To determine the suppressive effects of MPA on T-cell proliferation, and to assess the...

  3. Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs

    Full-text: Available

    | Contributor(s):: Lauri-Jo Gamble, Jordyn M Boesch, Christopher W Frye, Wayne S Schwark, Sabine Mann, Lisa Wolfe, Holly Brown, Erin S Berthelsen, Joseph J Wakshlag

    Objectives: The objectives of this study were to determine basic oral pharmacokinetics, and assess safety and analgesic efficacy of a cannabidiol (CBD) based oil in dogs with osteoarthritis (OA). Methods: Single-dose pharmacokinetics was performed using two different doses of CBD...

  4. Evaluation of pharmacokinetics and efficacy of ivermectin following oral administration in dogs against experimental infection of Ctenocephalides felis felis and Rhipicephalus sanguineus

    Full-text: Available

    | Contributor(s):: Magalhaes, V. S., Cid, Y. P., Ferreira, T. P., Medeiros, D. M. V., Batista, L. C. de S. O., Correia, T. R., Albert, A. L. M., Scott, F. B.

    With the increasing number of pets in home the human-animal relationship is increasingly close and care about control disease growing. Ivermectin (IVM) is frequently used because its proven safety. IVM is recommended for the treatment of demodectic scabies and prevention of heartworm in dogs, but...

  5. Animal-assisted therapy: New disinfectant list of DVG for "Established veterinary practice and animal shelters "Tiergestutzte Therapien: Neue Desinfektionsmittelliste der DVG fur die Bereiche "Niedergelassene Veterinarpraxis und Tierheime"

    | Contributor(s):: Rheinbaben, F. von, Werner, S.

    This article presents a list of some of the veterinary disinfectants/drugs recommended by the German Veterinary Society for private animal hospitals and animal shelters highlighting the indications, efficacy, metabolism, dosage effects, and pharmokinetics of each product.

  6. Simple cannulation procedure for serial blood sampling through cutaneous ulnar vein in chickens

    | Contributor(s):: Bayer, D. M., Mohan, K., Jayakumar, K., Manafi, M., Pavithra, B. H.

    The objective of the study was to collect repeated, low-stress blood samples from the ulnar vein of chickens required for pharmacokinetic studies or hormonal assays. The study used 5 apparently healthy, unsexed, commercial broiler chickens about 6 weeks old and weighing 1.7-1.9 kg for serial...

  7. The use of diazepam as a pharmacological validation of eye white as an indicator of emotional state in dairy cows

    | Contributor(s):: Sandem, A. I., Janczak, A. M., Salte, R., Braastad, B. O.

    This experiment aims at validating the percentage of visible white in the eye as an emotional indicator, related to the frustration-contentedness axis, in cattle. Earlier experiments showed that the calculated percentage of white in the eyes was larger in frustrated or scared cows compared to...