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Tags: Genes + Genetics

All Categories (1-20 of 24)

  1. Adenoviral Gene Transfer of Gremlin Modulates Vascular Endothelial Growth Factor-A-Induced Angiogenesis in Porcine Myocardium

    Contributor(s):: Pajula, J. J., Halonen, P. J., Hätinen, O. P., Ylä-Herttuala, S., Nurro, J.

  2. Protein expression and genetic variability of canine Can f 1 in golden and Labrador retriever service dogs

    Full-text: Available

    | Contributor(s):: Breitenbuecher, C., Belanger, J. M., Levy, K., Mundell, P., Fates, V., Gershony, L., Famula, T. R., Oberbauer, A. M.

    Background: Valued for trainability in diverse tasks, dogs are the primary service animal used to assist individuals with disabilities. Despite their utility, many people in need of service dogs are sensitive to the primary dog allergen, Can f 1, encoded by the Lipocalin 1 gene (LCN1). Several...

  3. Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs

    | Contributor(s):: Bridgett M. vonHoldt, Emily Shuldiner, Ilana Janowitz Koch, Rebecca Y. Kartzinel, Andrew Hogan, Lauren Brubaker, Shelby Wanser, Daniel Stahler, Clive D. L. Wynne, Elaine A. Ostrander, Janet S. Sinsheimer, Monique A. R. Udell

    Although considerable progress has been made in understanding the genetic basis of morphologic traits (for example, body size and coat color) in dogs and wolves, the genetic basis of their behavioral divergence is poorly understood. An integrative approach using both behavioral and genetic data...

  4. Genetic components of companion animal behavior

    | Contributor(s):: Jones, Paul, McCune, Sandra, Freund, Lisa S., Esposito, Layla, Gee, Nancy R., McCardle, Peggy

  5. Purebred dogs and canine wellbeing

    Full-text: Available

    | Contributor(s):: Jeppsson, S.

    Breeders of purebred dogs usually have several goals they want to accomplish, of which canine wellbeing is one. The purpose of this article is to investigate what we ought to do given this goal. Breeders typically think that they fulfil their wellbeing-related duties by doing the best they can...

  6. Canine olfactory genetics

    | Contributor(s):: Quignon, P., Robin, S., Galibert, F.

  7. Genetic diversity of canine olfactory receptors

    | Contributor(s):: Robin, S., Tacher, S., Rimbault, M., Vaysse, A., Dreano, S., Andre, C., Hitte, C., Galibert, F.

  8. Organization and expression of canine olfactory receptor genes

    Full-text: Available

    | Contributor(s):: Issel-Tarver, L., Rine, J.

    Four members of the canine olfactory receptor gene family were characterized. The predicted proteins shared 40-64% identity with previously identified olfactory receptors. The four subfamilies identified in Southern hybridization experiments had as few as 2 and as many as 20 members. All four...

  9. Heterogeneity and phylogenetic relationships of community-associated methicillin-sensitive/resistant Staphylococcus aureus isolates in healthy dogs, cats and their owners

    | Contributor(s):: Wan, M. T., Fu, S. Y., Lo, Y. P., Huang, T. M., Cheng, M. M., Chou, C. C.

    Aims: To investigate the distribution of staphylococcal enterotoxin genes (se) and the molecular features of community-associated methicillin-sensitive/resistant Staphylococcus aureus (CA-MSSA/MRSA) isolates in the nostrils of healthy pets and their owners. Methods and Results: A total of 114...

  10. Exploiting abstract possibilities: a critique of the concept and practice of product patenting

    | Contributor(s):: Radder, H.

    Developments in biotechnology and genomics have moved the issue of patenting scientific and technological inventions toward the centre of interest. In particular, the patentability of genes of plants, animals, or humans and of genetically modified (parts of) living organisms has been discussed,...

  11. Molecular characterization of methicillin-resistant Staphylococcus aureus strains from pet animals and their relationship to human isolates

    | Contributor(s):: Strommenger, B., Kehrenberg, C., Kettlitz, C., Cuny, C., Verspohl, J., Witte, W., Schwarz, S.

    Objectives: Methicillin-resistant Staphylococcus aureus (MRSA) isolates from pet animals were characterized and compared with human isolates from clonal complexes most prevalent in Central Europe. Methods: S. aureus isolates were investigated for their in vitro susceptibility to antimicrobial...

  12. Primate models in serotonin transporter research

    | Contributor(s):: Herman, Khalisa N., Winslow, James T., Suomi, Stephen J.

  13. Domestication - from behaviour to genes and back again

    | Contributor(s):: Jensen, P.

    During domestication, animals have adapted with respect to behaviour and an array of other traits. This tends to give rise to a specific domestication phenotype, involving similar changes in colour, size, physiology and behaviour among different species. Hence, domestication offers a model for...

  14. Genetics and genomics of animal behaviour and welfare - challenges and possibilities. (Special Issue: Farm animal welfare since the Brambell report.)

    | Contributor(s):: Jensen, P., Buitenhuis, B., Kjaer, J., Zanella, A., Mormede, P., Pizzari, T.

    Traditionally, the contribution of applied ethology to animal welfare science has concentrated on understanding the reactions of animals to their housing conditions. Domestication has had small effects on fundamental aspects of animal behaviour, and therefore, the needs of present day...

  15. An approach to canine behavioural genetics employing guide dogs for the blind

    | Contributor(s):: Takeuchi, Y., Hashizume, C., Arata, S., Inoue-Murayama, M., Maki, T., Hart, B. L., Mori, Y.

    The purpose of this study was to attempt to find related variables of the canine genome with behavioural traits of dogs maintained and tested in a guide dog facility which provided a relatively uniform environment. The study involved 81 Labrador Retrievers that were being trained as guide dogs....

  16. From society to genes with the honey bee

    | Contributor(s):: Robinson, Gene E.

  17. Animal models of eating disorder traits

    | Contributor(s):: Kas, Martien J. H., Adan, Roger A. H.

  18. Genetics and animal domestication: new windows on an elusive process

    | Contributor(s):: Dobney, K., Larson, G.

    Domesticated animals are universally familiar. How, when, where and why they became domesticated is less well understood. The genetic revolution of the past few decades has facilitated novel insights into a field that previously was principally the domain of archaeozoologists. Although some of...

  19. Uncertainties of nutrigenomics and their ethical meaning

    | Contributor(s):: Korthals, M., Komduur, R.

    Again and again utopian hopes are connected with the life sciences (no hunger, health for everyone; life without diseases, longevity), but simultaneously serious research shows uncertain, incoherent, and ambivalent results. It is unrealistic to expect that these uncertainties will disappear. We...

  20. Traits and genotypes may predict the successful training of drug detection dogs

    | Contributor(s):: Maejima, M., Inoue-Murayama, M., Tonosaki, K., Matsuura, N., Kato, S., Saito, Y., Weiss, A., Murayama, Y., Ito, S.

    In Japan, approximately 30% of dogs that enter training programs to become drug detection dogs successfully complete training. To clarify factors related to the aptitude of drug detection dogs and develop an assessment tool, we evaluated genotypes and behavioural traits of 197 candidate dogs. The...