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Tags: Genetically modified animals + Genetic engineering

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  1. Genetically modified laboratory animals - what welfare problems do they face?

    Contributor(s):: Buehr, M., Hjorth, P. J., Hansen, A. K., Sandoe, P.

    In this article, we respond to public concern expressed about the welfare of genetically modified (GM) non-human animals. As a contribution to the debate on this subject, we attempt in this article to determine in what situations the practice of genetic modification in rodents may generate...

  2. Phenotype characterization and welfare assessment of transgenic rodents (mice)

    Contributor(s):: Mertens, C., Rulicke, T.

    Methods of transgenesis in vertebrate animals in the laboratory involve the stable addition or selective substitution of defined genes into the germline. Although there is a continuous and remarkable development in transgenic technology-the quality of transgenes, gene-targeting vectors, and...

  3. Deconstructing the animal in search of the real

    | Contributor(s):: Aloi, G.

    This paper looks at the past ten years of art practice informed by the human–animal studies agenda in order to assess what has been thus far achieved and which issues may become central to the future artistic debate. It is divided into two main sections: the first takes into consideration...

  4. The Frankenstein syndrome : ethical and social issues in the genetic engineering of animals

    | Contributor(s):: Rollin, Bernard E.

  5. Developing the ethical Delphi. (Special Issue: Ethical tools.)

    | Contributor(s):: Millar, K., Thorstensen, E., Tomkins, S., Mepham, B., Kaiser, M.

    A number of EU institutions and government committees across Europe have expressed interest in developing methods and decision-support tools to facilitate consideration of the ethical dimensions of biotechnology assessment. As part of the work conducted in the EC supported project on ethical...

  6. Developing the Ethical Matrix as a decision support framework: GM fish as a case study. (Special Issue: Ethical tools.)

    | Contributor(s):: Kaiser, M., Millar, K., Thorstensen, E., Tomkins, S.

    The Ethical Matrix was developed to help decision-makers explore the ethical issues raised by agri-food biotechnologies. Over the decade since its inception the Ethical Matrix has been used by a number of organizations and the philosophical basis of the framework has been discussed and analyzed...

  7. Ethical analysis of the use of GM fish: emerging issues for aquaculture development. (Special Issue: Ethics and the politics of food.)

    | Contributor(s):: Millar, K., Tomkins, S.

    Improvements in production methods over the last two decades have resulted in aquaculture becoming a significant contributor to food production in many countries. Increased efficiency and production levels are off-setting unsustainable capture fishing practices and contributing to food security,...

  8. Genetic engineering and the integrity of animals

    | Contributor(s):: Vries, R. de

    Genetic engineering evokes a number of objections that are not directed at the negative effects the technique might have on the health and welfare of the modified animals. The concept of animal integrity is often invoked to articulate these kind of objections. Moreover, in reaction to the advent...

  9. Measuring biotechnology employees' ethical attitudes towards a controversial transgenic cattle project: the Ethical Valence Matrix

    | Contributor(s):: Small, B. H., Fisher, M. W.

    What is the relationship between biotechnology employees' beliefs about the moral outcomes of a controversial transgenic research project and their attitudes of acceptance towards the project? To answer this question, employees (n=466) of a New Zealand company, AgResearch Ltd., were surveyed...

  10. Risks associated with genetic modification: an annotated bibliography of peer reviewed natural science publications

    | Contributor(s):: Weaver, S. A., Morris, M. C.

    An annotated bibliography is presented of peer-reviewed papers highlighting the human health, animal welfare, and environmental risks (concerning biodiversity in particular) associated with genetic modification. The bibliography is organized according to the nature of the risks in question: (1)...

  11. Special Issue: Ethics and the politics of food. (Special Issue: Ethics and the politics of food.)

    | Contributor(s):: Lien, M. E., Anthony, R.

    This special issue examines how best to manage food production, distribution and consumption in an ethically viable manner. This issue consists of five papers. The first paper explains the differences between US and EU policies on genetically modified food and crops. The second paper explores the...

  12. Transgenesis in animal agriculture: addressing animal health and welfare concerns

    | Contributor(s):: Greger, M.

    The US Food and Drug Administration's final Guidance for Industry on the regulation of transgenesis in animal agriculture has paved the way for the commercialization of genetically engineered (GE) farm animals. The production-related diseases associated with extant breeding technologies are...

  13. The Frankenstein syndrome : ethical and social issues in the genetic engineering of animals

    | Contributor(s):: Rollin, Bernard E.

  14. Ethics and the genetic engineering of food animals

    | Contributor(s):: Thompson, P. B.

    This paper discusses the ethical issues raised by biotechnology applied to traditional food animals. The issues are separated into 3 categories; the transformation of pigs, sheep, cattle and other domesticated farm animals for purposes that deviate substantially from food production, including...

  15. Searching for the 'win-win'? Animals, genomics and welfare.

    | Contributor(s):: Twine, R.

    Animal Genomics sits within the nexus of the central contradiction that characterises human/animal relations within contemporary Western societies. On the one hand we can observe a historical move toward less instrumental human/animals relations and the emergence of ethics of care which have...

  16. Special issue: Fish Behaviour and Welfare.

    | Contributor(s):: Sneddon, L. U.

    This special issue contains topics on the welfare of fishes in the aquaculture and fishery industries, including aspects on behaviour, feeding, diseases, transgenesis and toxicology.

  17. Effects of growth hormone transgenes on the behavior and welfare of aquacultured fishes: a review identifying research needs. (Special issue: Fish Behaviour and Welfare.)

    | Contributor(s):: Hallerman, E. M., McLean, E., Fleming, I. A.

    Expression of a growth hormone (GH) transgene can achieve dramatic impacts upon the performance of aquaculture stocks, for example, increasing the growth rate of coho salmon 11-fold. With the prospect of improved production efficiency, some aquaculturists want to produce transgenic fish...

  18. Genetically modified animals in research: an analysis of applications submitted to ethics committees on animal experimentation in Sweden

    | Contributor(s):: Nordgren, A., Rocklinsberg, H.

    The use of genetically modified (GM) animals in biomedical research has increased during recent years and its ethical aspects have been subject to ongoing academic discussion. In order to reinforce this discussion, we analysed applications submitted to animal ethics committees in Sweden during...

  19. Outline of a risk assessment: the welfare of future xeno-donor pigs

    | Contributor(s):: Dahl, K., Sandoe, P., Johnsen, P. F., Lassen, J., Kornerup Hansen, A.

    The welfare of transgenic animals is often not considered prior to their generation. However, we demonstrated here how a welfare risk assessment can be carried out before transgenic animals are created. We describe a risk assessment identifying potential welfare problems in transgenic pigs...

  20. The Three Rs in the pharmaceutical industry: perspectives of scientists and regulators

    | Contributor(s):: Fenwick, N. P., Fraser, D.

    Six drug regulatory reviewers and 11 pharmaceutical industry scientists were interviewed to explore their perspectives on the obstacles and opportunities for greater implementation of the Three Rs (replacement, reduction, refinement) in drug research and development. Participants generally...